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Publikationsliste für
Julian Kager
als Autorin / Autor bzw. wesentlich beteiligte Person

52 Datensätze (2015 - 2021)


Zeitschriftenartikel


D. Ehgartner, T. Hartmann, S. Heinzl, M. Frank, L. Veiter, J. Kager, C. Herwig, J. Fricke:
"Controlling the specific growth rate via biomass trend regulation in filamentous fungi bioprocesses";
Chemical Engineering Science, 172 (2017), S. 32 - 41.

O. Goldbeck, D. Desef, K. Ovchinnikov, F. Perez-Garcia, J. Christmann, P. Sinner, P. Crauwels, J. Kager, C. Herwig et al.:
"Establishing recombinant production of pediocin PA-1 in Corynebacterium glutamicum";
Metabolic Engineering, 68 (2021), S. 34 - 45.

J. Kager, C. Herwig:
"Monte Carlo-Based Error Propagation for a More Reliable Regression Analysis across Specific Rates in Bioprocesses";
Bioengineering, 8 (2021), 160; 17 S.

J. Kager, C. Herwig:
"Simulieren, Observieren, Kontrollieren - Vorhersage des Wachstumsverhaltens von Penicillium chrysogenum";
GIT Labor-Fachzeitschrift, 62 (2018), 8; S. 32 - 34.

J. Kager, C. Herwig, I. Stelzer:
"State estimation for a penicillin fed-batch process combining particle filtering methods with online and time delayed offline measurements";
Chemical Engineering Science, 177 (2018), S. 234 - 244.

J. Kager, A. Tuveri, S. Ulonska, P. Kroll, C. Herwig:
"Experimental verification and comparison of model predictive, PID and model inversion control in a Penicillium chrysogenum fed-batch process";
Process Biochemistry, 90 (2020), S. 1 - 11.

J. Kopp, C. Slouka, D. Strohmer, J. Kager, O. Spadiut, C. Herwig:
"Inclusion Body Bead Size in E. coli Controlled by Physiological Feeding";
Microorganisms, 6 (2018), 13 S.

J. Kopp, C. Slouka, S. Ulonska, J. Kager, J. Fricke, O. Spadiut, C. Herwig:
"Impact of Glycerol as Carbon Source onto Specific Sugar and Inducer Uptake Rates and Inclusion Body Productivity in E. coli BL21(DE3)";
Bioengineering, 5 (2018), 1; 15 S.

P. Kroll, A. Hofer, S. Ulonska, J. Kager, C. Herwig:
"Model-Based Methods in the Biopharmaceutical Process Lifecycle";
Pharmaceutical Research, 34 (2017), 12; S. 2596 - 2613.

J. Pauk, J. Raju Palanisamy, J. Kager, K. Koczka, G. Berghammer, C. Herwig, L. Veiter:
"Advances in monitoring and control of refolding kinetics combining PAT and modeling";
Applied Microbiology and Biotechnology, 105 (2021), S. 2243 - 2260.

W. Reichelt, P. Thurrold, M. Brillmann, J. Kager, J. Fricke, C. Herwig:
"Generic biomass estimation methods targeting physiologic process control in induced bacterial cultures";
Engineering in Life Sciences, 16 (2016), 8; S. 720 - 730.

P. Sinner, J. Kager, S. Daume, C. Herwig:
"Model-based Analysis and Optimisation of a Continuous Corynebacterium glutamicum Bioprocess Utilizing Lignocellulosic Waste";
IFAC PapersOnLine, 52 (2019), 26; S. 181 - 186.

P. Sinner, M. Stiegler, C. Herwig, J. Kager:
"Noninvasive online monitoring of Corynebacterium glutamicum fed-batch bioprocesses subject to spent sulfite liquor raw material uncertainty";
Bioresource Technology, 321 (2021).

C. Slouka, J. Kopp, D. Strohmer, J. Kager, O. Spadiut, C. Herwig:
"Monitoring and control strategies for inclusion body production in E. coli based on glycerol consumption";
Journal of Biotechnology, 296 (2019), S. 75 - 82.

S. Ulonska, D. Waldschitz, J. Kager, C. Herwig:
"Model predictive control in comparison to elemental balance control in an E. coli fed-batch";
Chemical Engineering Science, 191 (2018), S. 459 - 467.

L. Veiter, J. Kager, C. Herwig:
"Optimal process design space to ensure maximum viability and productivity in Penicillium chrysogenum pellets during fed‑batch cultivations through morphological and physiological control";
Microbial Cell Factories, 19 (2020), 14 S.

R. Zimmerleiter, J. Kager, R. Nikzad-Langerodi, V. Berezhinskiy, F. Westad, C. Herwig, M. Brandstetter:
"Probeless non-invasive near-infrared spectroscopic bioprocess monitoring using microspectrometer technology";
Analytical and Bioanalytical Chemistry, 412 (2020), S. 2103 - 2109.


Buchbeiträge


S. Daume, J. Kager, C. Herwig:
"Time Resolved Sensitivity & Identifiability Analysis for Directed Parametrization of Highly Dynamic Models";
in: "Computer Aided Chemical Engineering, 29th European Symposium on Computer Aided Process Engineering", 46; Elsevier, 2019, ISBN: 978-0-12-818634-3, S. 1111 - 1116.

S. Daume, S. Kofler, J. Kager, P. Kroll, C. Herwig:
"Generic Workflow for the Setup of Mechanistic Process Models";
in: "Animal Cell Biotechnology", Springer Science + Business Media, 2020, ISBN: 978-1-0716-0190-7, S. 189 - 211.

J. Kager, V. Berezhinskiy, R. Zimmerleitner, M. Brandstetter, C. Herwig:
"Extension of a Particle Filter for Bioprocess State Estimation using Invasive and Non-Invasive IR Measurements";
in: "Computer Aided Chemical Engineering, 29th European Symposium on Computer Aided Process Engineering", 46; Elsevier, 2019, ISBN: 978-0-12-818634-3, S. 1417 - 1422.

P. Sinner, S. Daume, C. Herwig, J. Kager:
"Usage of Digital Twins Along a Typical Process Development Cycle";
in: "Digital Twins - Tools and Concepts for Smart Biomanufacturing", C. Herwig, R. Pörtner, J. Möller (Hrg.); Springer International Publishing, 2021, ISBN: 978-3-030-71659-2.

P. Sinner, C. Herwig, J. Kager:
"Time Scale Analysis and Optimization of a Continuous Microbial Bioprocess";
in: "Computer Aided Chemical Engineering, 30th European Symposium on Computer Aided Process Engineering", 48; S. Pierucci, F. Manenti, G. Bozzano, D. Manca (Hrg.); Elsevier B.V., 2020, ISBN: 978-0-1282-3377-1, S. 1603 - 1608.

I. Stelzer, J. Kager, C. Herwig:
"Comparison of Particle Filter and Extended Kalman Filter Algorithms for Monitoring of Bioprocesses";
in: "Proceedings of the 27th European Symposium on Computer Aided Process Engineering - ESCAPE 27", 40; A. Espuña, M. Graells, L. Puigjaner (Hrg.); Elsevier B.V., 2017, ISBN: 978-0-444-63965-3, S. 1483 - 1488.

S. Ulonska, J. Kager, C. Herwig:
"Automatic controller failure detection with application in model based control of an E. coli fed-batch";
in: "Computer-Aided Chemical Engineering, Vol. 43 - 28th European Symposium on Computer Aided Process Engineering Part A", A. Friedl, J. Klemes, S. Radl, P. Varbanov, T. Wallek (Hrg.); Elsevier B.V., 2018, ISBN: 978-0-444-64237-0, S. 1673 - 1678.


Vorträge und Posterpräsentationen (mit Tagungsband-Eintrag)


T. Hardiman, M. Hofinger, P. Ettinger, G. Kornfeld, M. Weiner, P. Wechselberger, J. Buchholz, W. Riethorst, W. Skibar, J. Kager, I. Stelzer, A. Golabgir, D. Ehgartner, C. Herwig:
"Implementierung einer Softsenser-basierten Regelung eines großtechnischen Fermentationsprozesses";
Vortrag: 13. Kolloquium Prozessanalytik: Prozessführung in der modernen Produktion, Esslingen, Deutschland; 21.11.2017 - 22.11.2017; in: "Programm", (2017), S. 50.

J. Kager:
"The deployment of mechanistic models in biotechnological production processes for advanced monitoring and control";
Vortrag: Corso di laurea in Ingegneria Chimica, Cagliari, Italien (eingeladen); 27.09.2018; in: "http://people.unica.it/ingegneriachimica/2018/09/26/avviso-seminario-julian-kager/", (2018), 1 S.

J. Kager, C. Herwig, V. Berezhinskiy:
"State estimation and control of bioprocesses based on mechanistic models";
Vortrag: IFPAC 2019 - 33rd International Forum and Exhibition on Process Analytical Chemistry (IFPAC) Annual Meeting, Washington D.C., USA; 03.03.2019 - 06.03.2019; in: "Abstracts", (2019), 1 S.

J. Kager, S. Ulonska, F. Pollesböck, C. Herwig:
"Engineer´s Playground: Interfacing Students and Bioreactors for Teaching and Research";
Vortrag: VSS 2018 - Vienna Young Scientists Symposium, Wien; 07.06.2018 - 08.06.2018; in: "VSS 2018", Book-of-Abstracts.com, (2018), ISBN: 978-3-9504017-8-3; S. 64 - 65.

J. Kopp, C. Slouka, S. Ulonska, J. Kager, J. Fricke, O. Spadiut, C. Herwig:
"Impact of glycerol as carbon source onto specific sugar and inducer uptake rates and inclusion body productivity in E. coli BL21 (DE3)";
Poster: 5th BioProScale Symposium, Berlin, Deutschland; 20.03.2018 - 22.03.2018; in: "Abstract Booklet", (2018), S. 48.

J. Kopp, C. Slouka, S. Ulonska, J. Kager, J. Fricke, O. Spadiut, C. Herwig:
"Impact of glycerol as carbon source onto specific sugar and inducer uptake rates and inclusion body productivity in E. coli BL21(DE3)";
Vortrag: ESBES 2018 - European Symposium on Biochemical Engineering Sciences, Lissabon, Portugal; 09.09.2018 - 12.09.2018; in: "Book of Abstracts", (2018), 1 S.

P. Kroll, S. Ulonska, J. Kager, C. Herwig:
"Ermöglichung kontinuierlicher Bioprozessführung durch Modelle, Data Science und PAT";
Vortrag: 13. Kolloquium Prozessanalytik: Prozessführung in der modernen Produktion, Esslingen, Deutschland (eingeladen); 21.11.2017 - 22.11.2017; in: "Programm", (2017), S. 39.

P. Sinner, J. Kager, S. Daume, C. Herwig:
"Model-based Analysis and Optimisation of a Continuous Corynebacterium glutamicum Bioprocess Utilizing Lignocellulosic Waste";
Vortrag: FOSBE 2019 - 8th IFAC Conference on Foundations of Systems Biology in Engineering, Valencia, Spanien; 15.10.2019 - 18.10.2019; in: "Program Booklet", (2019), S. 22 - 23.

I. Stelzer, J. Kager, C. Herwig:
"Application of particle filter algorithms for monitoring of bioprocesses";
Vortrag: CEN ISBS Vienna 2017, Joint Conference on Biometrics & Biopharmaceutical Statistics, Wien; 28.08.2017 - 01.09.2017; in: "Abstract Book", (2017), S. 82.


Vorträge und Posterpräsentationen (ohne Tagungsband-Eintrag)


S. Daume, J. Kager, C. Herwig:
"Time Resolved Sensitivity & Identifiability Analysis for Directed Parametrization of Highly Dynamic Models";
Poster: ESCAPE 29 - 29th European Symposium on Computer Aided Process Engineering, Eindhoven, Niederlande; 16.06.2019 - 19.06.2019.

C. Herwig, J. Kager:
"Digital Twin Based Optimization of cell cultures";
Vortrag: EFCE Spotlight Talks (Online Conference), Frankfurt am Main, Deutschland (eingeladen); 23.11.2020 - 04.12.2020.

J. Kager, V. Berezhinskiy, R. Zimmerleitner, M. Brandstetter, C. Herwig:
"Extension of a Particle Filter for Bioprocess State Estimation using Invasive and Non-Invasive IR Measurements";
Vortrag: ESCAPE 29 - 29th European Symposium on Computer Aided Process Engineering, Eindhoven, Niederlande; 16.06.2019 - 19.06.2019.

J. Kager, C. Herwig:
"Model based control of a penicillin production process";
Poster: BIOPRO World Talent Campus 2018, Sorø, Dänemark (eingeladen); 18.08.2018 - 22.08.2018.

J. Kager, I. Stelzer, C. Herwig:
"Improving Bioprocesses by Physiological Process Control";
Poster: Workshop on Methods for Accelerating Scalable Bioprocess Development, Wien; 09.11.2016 - 11.11.2016.

J. Kager, S. Ulonska, P. Kroll, C. Herwig:
"Multi-parametric Control of Bioprocesses using Mechanistic Models";
Poster: ProcessNet-Jahrestagung und 32. DECHEMA-Jahrestagung der Biotechnologen 2016, Aachen, Deutschland; 12.09.2016 - 15.09.2016.

P. Sinner, C. Herwig, J. Kager:
"Time scale analysis and optimization of a continuous microbial bioprocess";
Poster: ESCAPE 30 - 30th European Symposium on Computer Aided Process Engineering (Online Conference), Mailand, Italien; 30.08.2020 - 02.09.2020.

I. Stelzer, J. Kager, C. Herwig:
"Comparison of Particle Filter and Extended Kalman Filter Algorithms for Monitoring of Bioprocesses";
Poster: Symposium on Computer Aided Process Engineering - ESCAPE 27, Barcelona, Spanien; 01.10.2017 - 05.10.2017.

S. Ulonska, J. Kager, C. Herwig:
"Automatic controller failure detection with application in model based control of an E. coli fed-batch";
Vortrag: Escape28 - 28th European Symposium on Computer Aided Process Engineering, Graz; 10.06.2018 - 13.06.2018.


Patente


W. Reichelt, C. Herwig, J. Kager, P. Sagmeister, M. Funke:
"Improved fermentation process";
Patent: Europa, Nr. EP16158294.5; eingereicht: 02.03.2016.

W. Reichelt, C. Herwig, J. Kager, P. Sagmeister, M. Funke:
"Improved Fermentation Process";
Patent: International, Nr. Wo 2017/149065; eingereicht: 02.03.2017.


Dissertationen (eigene und begutachtete)


J. Kager:
"The Deployment of Mechanistic Models for Advanced Bioprocess Monitoring and Control";
Betreuer/in(nen), Begutachter/in(nen): C. Herwig, F. van der Berg, S. Jakubek; Institut für Verfahrenstechnik, Umwelttechnik und Technische Biowissenschaften, 2019; Rigorosum: 07.06.2019.


Diplom- und Master-Arbeiten (eigene und betreute)


V. Berezhinskiy:
"Comparison of different model-based observers for monitoring substrate and product concentrations in a Penicillium chrysogenum Fed-batch process";
Betreuer/in(nen): C. Herwig, J. Kager; Institut für Verfahrenstechnik, Umwelttechnik und Technische Biowissenschaften, 2019; Abschlussprüfung: 03.04.2019.

J. Kager:
"Physiological Bioprocess Control: Constant specific substrate uptake rate in an antibody producing E. coli expression platform";
Betreuer/in(nen): C. Herwig, W. Reichelt; Institut für Verfahrenstechnik, Umwelttechnik und Technische Biowissenschaften, 2015; Abschlussprüfung: 05.10.2015.

K. Lagoda:
"Bioprocess Control utilising Alternative Specific Rates";
Betreuer/in(nen): C. Herwig, J. Kager, D. Wibbing; Institut für Verfahrenstechnik, Umwelttechnik und Technische Biowissenschaften, 2021; Abschlussprüfung: 25.01.2021.

A. Tuveri:
"Model Based Control of Penicillium Chrysogenum Fed-Batch Process";
Betreuer/in(nen): C. Herwig, J. Kager, S. Tronci; Institut für Verfahrenstechnik, Umwelttechnik und Technische Biowissenschaften, 2018; Abschlussprüfung: 25.09.2018.


Wissenschaftliche Berichte


J. Kager, J. Fricke, U. Becken, C. Herwig:
"A Generic Biomass Soft Sensor and Its Application in Bioprocess Development";
Bericht für Eppendorf AG; Berichts-Nr. 357, 2017; 8 S.

J. Kager, C. Herwig, R. Holzer:
"imPACts Industrial Methods for Process Analytical Chemistry - From Measurement Technologies to Information Systems - "All-in-One: ein neuer Blick auf biochemische Prozesse"!";
Bericht für imPACts; 2017; 2 S.

J. Kager, P. Sinner, H. Müller, C. Herwig:
"Real-time estimation of fungal biomass based on off gas analysis";
Bericht für BlueSens GmbH; 2019; 4 S.