Publications in Scientific Journals:

L. Gherardini, C.M. Cousins, J.J. Hawkes, J. Spengler, S. Radel, H. Lawler, B. Devcic-Kuhar, M. Gröschl, W.T. Coakley, A.J. McLoughlin:
"A new Immobilisation method to arrange particles in a gel matrix by ultrasound standing waves";
Ultrasound in Medicine and Biology, 31 (2005), 2; 261 - 272.

English abstract:
Ultrasonic forces may be used to manipulate particles in suspension. For
example, a standing wave ultrasound (US) field applied to a suspension moves
the particles toward areas of minimal acoustic pressure, where they are
orderly retained creating a predictable heterogeneous distribution. This
principle of ultrasonic retention of particles or cells has been applied in
numerous biotechnological applications, such as mammalian cell filtering and
red blood cell sedimentation. Here, a new US-based cell immobilisation
technique is described that allows manipulation and positioning of
cells/particles within various nontoxic gel matrices before polymerisation.
Specifically, gel immobilisation was used to directly demonstrate that the
viability of yeast cells arranged by an US standing wave is maintained up to
4 days after treatment. The versatility of this immobilisation method was
validated using a wide range of acoustic devices. Finally, the potential
biotechnological advantages of this US-controlled particle positioning
method combined with gel immobilisation/encapsulation technology are

Online library catalogue of the TU Vienna:

Created from the Publication Database of the Vienna University of Technology.