[Zurück]

M. Xu, D.S. Peterson, T. Rohr, F. Svec, J.M.J. Frechet:
"Polar polymeric stationary phases for normal-phase HPLC based on monodisperse macroporous poly(2,3-dihydrxypropyl methacrylate-co-ethylene dimethacrylate) beads";
Analytical Chemistry, 75 (2003), S. 1011 - 1021.

The effect of variables such as shape template size, porogen compn. and percentage, content of crosslinking monomer, and polymn. temp. on the properties of uniformly sized 3-μm porous poly(glycidyl methacrylate-co-ethylene dimethacrylate) beads prepd. by the staged templated suspension polymn. technique was studied. The porous properties of the beads including surface morphol., pore size distribution, and sp. surface area were optimized to obtain highly efficient stationary phases for normal-phase HPLC. A column packed with diol stationary phase obtained by hydrolysis of poly(glycidyl methacrylate-co-ethylene dimethacrylate) beads affords an efficiency of 67,000 plates/m for toluene using THF as the mobile phase. The retention properties and selectivity of the diol beads are easily modulated by changes in the compn. of the mobile phase. The performance of these beads is demonstrated with the sepns. of a variety of polar compds. including positional isomers, aniline derivs., and basic tricyclic antidepressant drugs.

http://aleph.ub.tuwien.ac.at/F?base=tuw01&func=find-c&ccl_term=AC04405108