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U. Mueller, M. Eberle, C. Pillonel, W. Lutz, P. Stanetty:
"Preparation of thiazol substituted aminopyrimidines as plant protection agents";
Patent: PCT, Nr. WO 2003029249; eingereicht: 19.09.2002, erteilt: 10.04.2003.

The title compds. [I; R1 = H, alkyl, cycloalkyl, etc.; R2 = H, alkyl, haloalkyl, etc.; NR1R2 = (un)substituted (un)satd. ring which may contain O or S as a ring member, or form N:CR9NR10R11; R3 = H, halo, alkyl; R4 = H, alkyl, haloalkyl, etc.; R5 = H, OH, halo, etc.; R6 = H, alkyl, haloalkyl; R7 = (un)substituted thienyl, pyridyl, aryl; R8 = H, alkyl, alkenyl, etc.; R9 = H, alkyl, haloalkyl, etc.; R10 = alkyl, haloalkyl, alkoxyalkyl, etc.; R11 = alkyl, cycloalkyl, aryl, etc.], useful as fungicides, were prepd. Thus, a multi-step synthesis of I [NR1R2 = N:C(Me)NMe2; R3-R6 = H; R7 = Ph; R8 = H], starting from 4-methyl-2-methylthiopyrimidine and Me benzoate, was given. The compds. I showed good activity in twelve different tests (biol. data given).