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P Hinsmann, L. Arce, P. Svasek, M. Lämmerhofer, B. Lendl:
"Separation and on-line distinction of enantiomers - A non-aqueous capillary electrophoresis Fourier transform infrared spectroscopy study";
Applied Spectroscopy, 58 (2004), 662 - 667.

We report on the separation and on-line distinction of (R,S)-3-5-dinitrobenzoyl leucine (DNB-Leu) enantiomers with non-aqueous capillary electrophoresis (CE) and Fourier transform infrared spectroscopic (FT-IR) detection using O-(tert-butyl carbamoyl) quinine (tBuCQN) as chiral selector (CS). Due to intermolecular interactions - particularly ionic interactions, hydrogen bonding and p-p-interactions - the enantiomers undergo enantioselective complex and ion-pair formation, respectively with the CS enabling CE separation and direct identification with FT-IR detection. Especially the S-enantiomer of the analyte shows significant changes in the mid-IR region upon complexation allowing for a clear spectral distinction between both enantiomers. In that way FT-IR spectroscopy represents a novel attractive detection method for CE enantiomeric separations providing stereochemical information on the interactions between the chiral selector and the enantiomers, which is hardly accessible by other CE detection methods.

http://aleph.ub.tuwien.ac.at/F?base=tuw01&func=find-c&ccl_term=AC04969541