Vorträge und Posterpräsentationen (mit Tagungsband-Eintrag):
P. Knesl, U. Jordis:
"Synthesis of Sulfapyridine metabolites";
Poster: 8th International Electronic Conference on Synthetic Organic Chemistry,
Internet;
01.11.2004
- 30.11.2004; in: "8th International Electronic Conference on Synthetic Organic Chemistry",
(2004),
Paper-Nr. C004.
Kurzfassung englisch:
Sulfapyridine (SP) is an antibacterial compound that is used as such and also the active metabolite of sulfosalzazine (SASP) which shows antiphlogistic, antibacterial and immunomodulatoric properties. Sulfapyridine is also used to help control dermatitis herpetiformis (Duhring's disease), a skin problem. It has been reported, that sulfapyridine is metabolized to 5-hydroxysulfapyridine but no synthesis of this proposed metabolite has been published.We will report on the synthesis of thia and other potential metabolites of sulfapyridine.
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