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Zeitschriftenartikel:

U. Jordis, F. Sauter, S. Siddiqi, B. Küenburg, K. Bhattacharya:
"Synthesis of (1R,4R)- and (1S,4S)-2,5-diazabicyclo[2.2.1]heptanes and their N-substituted derivatives";
Synthesis, 10 (1990), S. 925 - 930.



Kurzfassung englisch:
Derivs. of the (1R,4R)- and (1S,4S)-2,5-diazabicyclo[2.2.1]heptane ring system I and II are prepd. in enantiomerically pure form via cyclization of proline derivs. III and IV (R = p-MeC6H4SO2) with MeNH2. The target compds. are precursors of antibacterial quinolone carboxylic acids.


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