Publications in Scientific Journals:
B. Kräutler, T. Dérer, P. Liu, W. Mühlecker, M. Puchberger, K. Gruber, C. Kratky:
"Oligomethylene-Bridged Vitamin B12 Dimers";
Angewandte Chemie - International Edition,
34
(2003),
1;
84
- 86.
English abstract:
The reaction of the highly nucleophilic CoI form of vitamin B12 with 1, -dibromo-n-alkanes (>=4) leads to oligomethylene-bridged B12 dimers in high yields. Use of 1,4-dibromobutane results in a dimer (shown schematically on the right), in which the two cobalamin moieties are tightly packed and coaxially linked through a tetramethylene chain, which is a synclinal conformation.
Keywords:
alkanediyl-bridged complexes ; cobalt compounds ; vitamin B12
"Official" electronic version of the publication (accessed through its Digital Object Identifier - DOI)
http://dx.doi.org/10.1002/anie.199500841
Created from the Publication Database of the Vienna University of Technology.