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B. Hametner, J. Kropf, C. Mayer, B. Eber, T. Weber, S. Wassertheurer:
"Pulse Wave Separation: A Comparison of Methods";
Talk: EUROSIM 2010 - 7th Congress on Modelling and Simulation, Prague, Czech Republic; 2010-09-06 - 2010-09-10; in: "Proceedings of the 7th Congress on Modelling and Simulation", M. Snorek, Z. Buk, M. Cepek, J. Drchal (ed.); Vol.2 Full Papers (2010), ISBN: 978-80-01-04589-3; 932 - 938.

In the last years new concepts such as pulse wave analysis (PWA) have emerged to determine cardiovascular risk. In PWA the augmentation of the aortal blood pressure due to reflections in the arterial system is expressed by the augmentation index or the augmentation pressure. One of the drawbacks of these parameters is their dependence on the timing of the reflected pressure waves. This problem can be overcome with the concept of wave separation analysis (WSA), which is carried out in the frequency domain and separates the measured pressure wave into forward and backward going waves. Another method for wave separation is known as wave intensity analysis (WIA), which is based on the methods of characteristics and is operating in the time domain.
The aim of this work is to compare the wave separation analysis method and the wave intensity analysis method by looking at several parameters derived from the separated pulse waves based on a study population of 131 patients.
For the backward pressure wave (Pb) the mean amplitude using WSA is 16.26 (± 5.13) mmHg and with WIA 16.16 (± 5.12) mmHg. The mean reflection magnitude (RM) using WSA is 0.626 (± 0.099) and with WIA 0.616 (± 0.096).
The results of this study give a good basis to fully accept wave intensity analysis as an alternative method to perform pulse wave separation.

pulse wave analysis, wave separation analysis, wave intensity analysis