Zeitschriftenartikel:
A. Kolarovic, M. Schnürch, M.D. Mihovilovic:
"Tandem Catalysis: From Alkynoic Acids and Aryl Iodides to 1,2,3-Triazoles in One Pot";
Journal of Organic Chemistry,
76
(2011),
8;
S. 2613
- 2618.
Kurzfassung englisch:
A tandem catalysis protocol based on decarboxylative coupling of alkynoic acids and 1,3-dipolar cycloaddition of azides enables a highly efficient synthesis of a variety of functionalized 1,2,3-triazoles. The three-step, one-pot method avoids usage of gaseous or highly volatile terminal alkynes, reduces handling of potentially unstable and explosive azides to a minimum, and furnishes target structures in excellent yields and a very good purity without the need for additional purification.
Schlagworte:
tandem catalysis, click chemistry, decarboxylative coupling
"Offizielle" elektronische Version der Publikation (entsprechend ihrem Digital Object Identifier - DOI)
http://dx.doi.org/10.1021/jo1024927
Erstellt aus der Publikationsdatenbank der Technischen Universität Wien.