[Zurück]

C. Urach, G. Zauner, I. Wilbacher, F. Breitenecker:
"Model selection process for cost effectiveness analysis of an organized AAA screening in austria";
in: "ISPOR 15th Annual European Congress", herausgegeben von: International Society for Pharmacoeconomics and Outcomes Research; Elsevier, Lawrenceville, USA, 2012, ISSN: 1098-3015, S. 473 - 474.

OBJECTIVES: As part of the IFEDH (Innovative Framework for Evidence based Decision
making in Healthcare) research project (FFG grant number 827347) a cost
effectiveness analysis of systematic population based screening for abdominal
aortic aneurysm (AAA) in Austria has to be performed. The modeling method selection
process is conducted in detail, taking into account the possible influence of
chronic disease, smoking and gender. METHODS: In parallel three different strategies
are performed. The first one is a non systematic literature research on AAA
screening modeling concepts in Europe. The second deals with modeling concepts
available in the research project, mainly Markov models, agent based modeling
techniques and System Dynamics. The third part deals with a data overview from
Austrian Health service providers, identifying risk factors to be taken into account
as well as literature research on this topic. Based on the described tasks an interdisciplinary
group from the field of HTA, data quality assessment, mathematical
modeling and statistics choose the best suited modeling concept. RESULTS: Based
on the identified literature on AAA screening modeling, the analyzed situation
regarding smoking behavior and chronic diseases as well as technical classification
of the benefits of the different methods an agent based simulation model has been
chosen. Detailed modeling concepts are developed and the implementation phase
is started. Due to the bottom-up approach the original data can be implemented
without transformations, leading to higher reliability. CONCLUSIONS: The development
of modern modeling methods in the IFEDH project in advance as well as
setting up an interdisciplinary team leads to higher performance regarding overall
project working time, quality in the decision process and realization of an AAA
screening model for Austria. Agent based modeling techniques are identified as most flexible and well suited in the Austrian context.