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Zeitschriftenartikel:

D. Bianchi, R. Moran-Ramallal, N. Iqbal, F. Rudroff, M.D. Mihovilovic:
"Enantiocomplementary access to carba-analogs of C-nucleoside derivatives by recombinant Baeyer-Villiger monooxygenases";
Bioorganic & Medicinal Chemistry Letters, 23 (2013), S. 2718 - 2720.



Kurzfassung englisch:
A novel and stereoselective synthetic route towards carba-C-nucleosides was investigated applying an
enantiodivergent biooxidation strategy by two different Baeyer-Villiger monooxygenases. Within only
three chemo-enzymatic steps it was possible to introduce four chiral centers starting from commercially
available non-chiral starting material.

Schlagworte:
Baeyer-Villiger monooxygenase, C-Nucleoside, Carba-showdomycin, Carba-C-nucleoside


"Offizielle" elektronische Version der Publikation (entsprechend ihrem Digital Object Identifier - DOI)
http://dx.doi.org/10.1016/j.bmcl.2013.02.085


Erstellt aus der Publikationsdatenbank der Technischen Universität Wien.