Publications in Scientific Journals:
D. Bianchi, R. Moran-Ramallal, N. Iqbal, F. Rudroff, M.D. Mihovilovic:
"Enantiocomplementary access to carba-analogs of C-nucleoside derivatives by recombinant Baeyer-Villiger monooxygenases";
Bioorganic & Medicinal Chemistry Letters,
23
(2013),
2718
- 2720.
English abstract:
A novel and stereoselective synthetic route towards carba-C-nucleosides was investigated applying an
enantiodivergent biooxidation strategy by two different Baeyer-Villiger monooxygenases. Within only
three chemo-enzymatic steps it was possible to introduce four chiral centers starting from commercially
available non-chiral starting material.
Keywords:
Baeyer-Villiger monooxygenase, C-Nucleoside, Carba-showdomycin, Carba-C-nucleoside
"Official" electronic version of the publication (accessed through its Digital Object Identifier - DOI)
http://dx.doi.org/10.1016/j.bmcl.2013.02.085
Created from the Publication Database of the Vienna University of Technology.