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A. Karabegovic, M. Hinteregger, C. Janeczek, W. Reichenfelser, M. Gföhler:
"A Systemic Mock Circulation for In-Vitro Testing of a Pneumatically Operated Left Ventricular Assist Device";
Vortrag: 19th IFAC World Congress, Cape Town, South Africa; 24.08.2014 - 29.08.2014; in: "Proceedings of the 19th IFAC World Congress, 2014", A. Karabegovic (Hrg.); (2014), ISBN: 978-3-902823-62-5; S. 8409 - 8414.

This work presents the development of a systemic mock circulation loop designed for testing of an axial flow, pneumatically operated left ventricular assist device (LVAD). A simulation of the heart proximal systemic circulation has been implemented that resembles the environment in which the LVAD will be operating, from where a hydraulic system, with several reconsiderations, has been constructed. An alternative method for measurement of the pulsatile aortic flow is suggested. A significant match between the simulated and measured system responses is demonstrated which substantially simplifies the search for parameter sets that determine the hemodynamic behavior of the system. Due to a high degree of flexibility and a wide range of hemodynamic states that can be simulated, the presented mock circulation is suitable for in-vitro experiments with the LVAD.

Physiological Model; Model formulation, experiment design; Developments in measurement, signal processing

http://dx.doi.org/10.3182/2014

http://publik.tuwien.ac.at/files/PubDat_237057.pdf