Publications in Scientific Journals:

M. Bucko, P. Gemeiner, A. Schenkmayerova, T. Krajcovic, F. Rudroff, M.D. Mihovilovic:
"Baeyer-Villiger oxidations: biotechnological approach";
Applied Microbiology and Biotechnology, 100 (2016), 15; 6585 - 6599.

English abstract:
Baeyer-Villiger monooxygenases (BVMOs) are a
very well-known and intensively studied class of flavin-
dependent enzymes. Their substrate promiscuity, high chemo-, regio-, and enantioselectivity are prerequisites for the
use in synthetic chemistry and should pave the way for successful industrial processes. Nonetheless, only a very limited
number of industrial relevant transformations are known,
mainly due to the lack of BVMOs stability and cofactor de-
pendency. In this review, we focus on novel BVMO-mediated
transformations, BVMOs in cascade type reactions, potential
industrial applications, and how limitations have been tackled
by the community. Special attention will be put on whole-cell
immobilization strategies.We emphasize to bridge recent developments in fundamental research to industrial applications.

Baeyer-Villigermonooxygenases . Cascade reactions .Whole-cell immobilization . Polyelectrolyte complex capsules .Asymmetric synthesis . Biocatalysis

"Official" electronic version of the publication (accessed through its Digital Object Identifier - DOI)

Electronic version of the publication:

Created from the Publication Database of the Vienna University of Technology.