Talks and Poster Presentations (with Proceedings-Entry):
M. Reisacher, M. Le Muzic, I. Viola:
"CellPathway: A Simulation Tool for Illustrative Visualization of Biochemical Networks";
Talk: WSCG: International Conference in Central Europe on Computer Graphics, Visualization and Computer Vision,
- 2016-06-03; in: "WSCG proceedings",
The molecular knowledge about complex biochemical reaction networks in biotechnology is crucial and has received a lot of attention lately. As a consequence, multiple visualization programs have been already developed to illustrate the anatomy of a cell. However, since a real cell performs millions of reactions every second to sustain live, it is necessary to move from anatomical to physiological illustrations to communicate knowledge about the behavior of a cell more accurately. In this thesis I propose a reaction system including a collision detection algorithm, which is able to work at the level of single atoms, to enable precise simulation of molecular interactions. To visually explain molecular activities during the simulation process, a real-time glow effect in combination with a clipping object have been implemented. Since intracellular processes are performed with a set of chemical transformations, a hierarchical structure is used to illustrate the impact of one reaction on the entire simulation. The CellPathway system integrates acceleration techniques to render large datasets containing millions of atoms in real-time, while the reaction system is processed directly on the GPU to enable simulation with more than 1000 molecules. Furthermore, a graphical user interface has been implemented to allow the user to control parameters during simulation interactively.
Electronic version of the publication:
Created from the Publication Database of the Vienna University of Technology.