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Buchbeiträge:

T. Linder, M. Schnürch, M.D. Mihovilovic:
"Construction Of Heterocyclic Lignans In Natural Product Synthesis And Medicinal Chemistry";
in: "Targets in Heterocyclic Systems", 19; O. Attanasi, P. Merino, D. Spinelli (Hrg.); Italian Chemical Society, 2016, ISBN: 978-88-86208-77-2, S. 274 - 298.



Kurzfassung englisch:
Oxygen-containing heterocyclic lignans are chiral molecules for which a variety of preparative methods exist and which displays numerous biological activities. Hence, efforts towards their syntheses are highly important. Due to the diversity of this class of natural products, the usefulness of a given synthetic approach will depend strongly on the particular type of lignan that is aimed for. This chapter explains the classification of lignans and highlights examples of laboratory preparation, discussing the stereoselectivity
and modularity of the synthetic routes for which a range of very different ideas are brought to bear. The motivation for work in this field often derives from the biological activity of these compounds, an aspect which is commented on as well.


"Offizielle" elektronische Version der Publikation (entsprechend ihrem Digital Object Identifier - DOI)
http://dx.doi.org/10.17374/targets.2016.19.274


Erstellt aus der Publikationsdatenbank der Technischen Universität Wien.