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Talks and Poster Presentations (with Proceedings-Entry):

C. Wytrzens, B. Hametner, S. Wassertheurer, F. Breitenecker:
"Simulation of the Pulmonary Circulation - Comparison of Different Modelling Approaches";
Talk: 5th Annual International Conference on Business, Technology and Innovation, Durres, Albanien; 2016-10-28 - 2016-10-30; in: "Proceedings of the 5th Annual International UBT Conference on Business, Technology and Innovation", E. Hajrizi (ed.); UBT - Higher Educations Institution, 5/Durres (2016), ISBN: 978-9951-437-39-4; 69 - 70.

English abstract:
Abstract. Pulmonary hypertension is a severe disease and can even lead to
heart failure. Therefore it is important that the knowledge about pressure and
flow waveforms in the pulmonary circulation is improved, which is the aim of
mathematical models. Over the last decades different kinds of mathematical
models were applied to simulate blood pressures and flows in the pulmonary
circulation. In this work we are looking at three different approaches of
mathematical models used in different studies in the past and are trying to
compare them. The first model, we will look at is the Windkessel model, which
is often related to an electrical circuit. The Windkessel model is a good
approach, if one is interested in the variation of the pressure only over time and
not in terms of location. Secondly, the Womersley solutions based on linearised
Navier Stokes equations are taken into account. Compared to the Windkessel
model, they take spatial distribution of pressure and flow in the vessels as well
as reflections into account. Furthermore, we are also considering the onedimensional
nonlinearised Navier-Stokes equations. In this approach, a
structured tree is often used as boundary condition to model the small arterioles,
capillaries and even venules. Via this structured trees characteristics of the
pulmonary circulation especially in the regions of the small vessels can be
investigated. Each of this approaches has its pros and cons in terms of applying
it to the pulmonary circulation. So depending on the detailedness of modelling
and simulating the pulmonary circulation, different types of models should be
considered.

Electronic version of the publication:

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