Zeitschriftenartikel:
N. Kratena, G. Gmeiner, V. Enev, P. Gärtner:
"Synthesis of 17β-hydroxymethyl-17α-methyl-18-norandrosta-1,4,13- trien-3-one: a long-term metandienone metabolite";
Steroids,
115
(2016),
S. 75
- 79.
Kurzfassung englisch:
The goal of this work was a good-yielding chemical synthesis of a metandienone metabolite which is of
interest in doping analysis. 20bOH-NorMD (IUPAC: 17b-hydroxymethyl-17a-methyl-18-norandrosta-1,4,13-triene-3-one) has been identified as a long-term urinary metabolite which can be detected and attributed to metandienone up to almost 3 weeks after exposure. The chemical synthesis of its epimer 20aOH-NorMD has been described before, as was an enzymatic synthesis of 20bOH-NorMD, but no chemical synthesis was published
Schlagworte:
Metandienone, Metabolism, Wagner-Meerwein rearrangement
"Offizielle" elektronische Version der Publikation (entsprechend ihrem Digital Object Identifier - DOI)
http://dx.doi.org/10.1016/j.steroids.2016.08.013
Erstellt aus der Publikationsdatenbank der Technischen Universität Wien.