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A. Ovsianikov:
"Multiphoton Lithography - Laser-based 3D-Printing with high spatial resolution";
Talk: 2017 International Forum on Innovation and Emerging Industries Development (IEID 2017), Shanghai; 2017-11-07 - 2017-11-09.

Additive manufacturing technologies, also referred to as 3D printing, are experiencing rapid development by providing disruptive solutions for different applications. In the recent years, multiphoton lithography (MPL) emerged as a 3D printing method allowing to achieve feature size down to 100 nm level [1]. This method utilizes photochemistry induced by multiphoton absorption of ultra-short laser pulses. Depending on the material MPL can produce high-resolution volumetric structures, induce photodegradation or spatially resolved covalent binding of specific molecules in the volume of the sample. Fabrication of complex high resolution constructs in accordance to a computer-aided design (CAD) model is especially attractive for designing of 3D cell-culture matrices for biological and tissue engineering applications [2]. Fabrication of 2D microstructured substrates, complex 3D scaffolds, containing actively induced topographies, and immobilization of biomolecules in a spatially defined manner was demonstrated with MPL. This presentation will review the recent progress of MPL for engineering and biomedical applications, as well as discuss the technological challenged of this technology on the way to widespread industrial applications.

1. Multiphoton Lithography: Techniques, Materials, and Applications, J. Stampfl, R. Liska, A. Ovsianikov (Eds.) John Wiley & Sons (2016), [ISBN: 978-3-527-33717-0]
2. A. Ovsianikov, V. Mironov, J. Stampf, and R. Liska, Engineering 3D cell-culture matrices: multiphoton processing technologies for biological and tissue engineering applications, Expert Rev. Med. Devices 9(6), 613-633 (2012) [doi:10.1586/erd.12.48]