Zeitschriftenartikel:
M. Spettel, R. Pollice, M. Schnürch:
"Quaternary Ammonium Salts as Alkylating Reagents in C−H Activation Chemistry";
Organic Letters,
19
(2017),
S. 4287
- 4290.
Kurzfassung englisch:
A rhodium(I)-catalyzed alkylation reaction of benzylic amines via C(sp3)−H activation using quaternary
ammonium salts as alkyl source is described. The reaction proceeds via in situ formation of an olefin via Hofmann elimination,
which is the actual alkylating reagent. This represents an operationally simple method for substituting gaseous and liquid olefins
with solid quaternary ammonium salts as alkylating reagents, which is transferable to other C−H activation protocols as well.
Schlagworte:
C-H activation, Rhodium, Alkylation, Hofmann Elimination
"Offizielle" elektronische Version der Publikation (entsprechend ihrem Digital Object Identifier - DOI)
http://dx.doi.org/10.1021/acs.orglett.7b01946
Erstellt aus der Publikationsdatenbank der Technischen Universität Wien.