Talks and Poster Presentations (with Proceedings-Entry):
R. Hasani, V. Beneder, M. Fuchs, D. Lung, R. Grosu:
"SIM-CE: An Advanced Simulation Platform for Studying the brain of Caenorhabditis elegans";
Talk: Workshop on Computational Biology at the 34th International Conference on Machine Learning(ICML), 2017,
2017-08-10; in: "Proceedings of the Workshop on Computational Biology at the 34th International Conference on Machine Learning(ICML), 2017",
We introduce SIM-CE, an advanced, user-friendly modeling and
simulation environment in Simulink for performing multi-scale be-
havioral analysis of the nervous system of Caenorhabditis elegans (C.
elegans). SIM-CE contains an implementation of the mathematical
models of C. elegansīs neurons and synapses, in Simulink, which
can be easily extended and particularized by the user. The Simulink
model is able to capture both complex dynamics of ion channels and
additional biophysical detail such as intracellular calcium concentra-
tion. We demonstrate the performance of SIM-CE by carrying out
neuronal, synaptic and neural-circuit-level behavioral simulations.
We show that Such environment enables the user to capture unknown
properties of the neural circuits, test hypotheses and determine the
origin of many behavioral plasticities exhibited by the worm such as
neuronal habituation, a simple non-associative learning mechanism.
Electronic version of the publication:
Created from the Publication Database of the Vienna University of Technology.