[Zurück]

M. Ebner, K. Parker, T. Vercauteren, S. Ourselin, S. Wassertheurer, A. Hughes, B. Hametner:
"Reservoir Pressure Separation at Brachial, Carotid and Radial arteries: A Quantitative Comparison and Evaluation";
Vortrag: Artery Conference 2017, Pisa; 12.10.2017 - 14.10.2017; in: "Artery Conference 2017", J. Cockroft, S. Laurent, C. Vlachopoulos (Hrg.); Artery 2017, 20/Elsevier (2017), ISSN: 1872-9312; S. 54 - 55.

Background
At present, reservoir pressur parameters are derived from arterial pressure waveforms regardless of the location of measurement. However, a comparison between sites has not been mad, and site-related differences may affect interpretations. In this study, we computed reservoir pressure waveform separations on hypertensive individuals where brachial, carotid and radial pressure measurements were available and quantitatively assessed their results.
Methods
95 participants in the Anlgo-Scandinavian Cardiac Outcomes Trial (ASCOT) had sequential measurements of pressure and flow velocity waveforms from carotid, brachial and radial arteries [1]. Pre-processing was performed to impose identical diastolic and mean blood pressures at all performed [2,3]. Systolic durations were estimated based on minimum pressure waveform derivatives.
Reservoir curves characterized by physiologically implausible parameters, i.e. a rate constant b < 0 or an asymptotic pressure P, were discarded, leaving 74 subjects with valid reservoir pressure waveforms at all three arterial locations.
Results
Estimated reservoir parameters are shown in Table 1. We observed significant differences between arteries in almost all parameters. A high correlation was observed between reservoir pulse pressure and reservoir pressure area at all locations, and the correlation between brachial and radial arteries was stronger for all parameters

http://dx.doi.org/10.1016/j.artres.2017.10.034