Talks and Poster Presentations (with Proceedings-Entry):
B. Hametner, C. Mayer, K Whitelegg, T. Weber, P. Fitscha, S. Wassertheurer:
"Sex differences in ambulatory central blood pressure and pulse wave reflections in untreated patients";
Talk: Artery Conference 2017,
- 2017-10-14; in: "Artery Conference 2017",
J. Cockroft, S. Laurent, C. Vlachopoulos (ed.);
Objectives: Sex differences for parameters of arterial wave reflection and arterial stiffness were reported from single office measurements, but circadian patterns were not extensivelx investigated up to now. The aim of this study was to determine sex differences between day and night values of ambulatory central blood pressure as well as ambulatory pulse wave parameters related to arterial wave reflection.
Methods. A Mobil-O-Graph (IEM, Stolberg) will inbuilt PWA technology was used in patients without anthihypertensive treatment visiting a doctor's pratice for internal medicine. Aortic blood pressure was obtained using a generalized tranfer function incorporating mean blood pressure for pressure calibration. Daytime was defined between 9 am and 8 pm and nighttime between 10 pm and 6 am.
Results. In the study 192 men /mean age 50.5 years) and 155 women (57.3 years) were included. men had higher central systolic (cSBP) and diastolic blood pressures compared to women. In contrast, augmentation index (Alx) and reflcetion magnitude (RM) were significantly lower in men compared to women both during day and night. For both sexes, Alx and RM were higher during the night, see table for full details (all day-night differences were statisticalle sighificant)
Conclusions: A typical blood pressure dipping during nighttime was found for both sexes. however, an increase in wave reflection parameters was found during nighttime leading to highest values for women during the night. Thus, single measurements have to be interpreted with cautiom and an ambulatory blood pressure measurement including pulse wave analysis might be beneficial.
"Official" electronic version of the publication (accessed through its Digital Object Identifier - DOI)
Created from the Publication Database of the Vienna University of Technology.