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S. Helfert, J. Hellmeier, E. Sevcsik, R. Liska, S. Baudis:
"Tailor-made Polymer Interfaces - Surfaces on Demand";
Vortrag: VSS 2018 - Vienna Young Scientists Symposium, Wien; 07.06.2018 - 08.06.2018; in: "VSS 2018", Book-of-Abstracts.com, (2018), ISBN: 978-3-9504017-8-3; S. 84 - 85.

The design and creation of particular interfaces between substrate surfaces and biomolecules became very attractive for research purposes and applications in the biomedical field[1]. The concept of building interfaces can be used for the manufacturing of biosensing platforms[2] (Figure 1), cell culturing, tissue engineering[3] and other fields, like cell research. In the last-mentioned area, applying the proper interface can yield profound information about the investigated species. A method for the design of such interfaces is the coating with functionalized polymer chains and covalently attached to a substrates surface, these organic linker molecules are then usually called polymer-brushes. To create such polymer interfaces, reversible addition-fragmentation chain transfer polymerization (RAFT) can be applied and the advantages of this polymerization technique are well defined polymers referring to the molecular weight or chain length distribution and a broad spectrum of compatible monomers[4] which gives the polymer chains particular properties. Custom end-groups can be introduced via application of the right chemical processes[5] and all these options make RAFT polymerization a powerful tool in the creation of custom-built complex architectures[6] with the desired chemical properties for biomedical applications[7].

Tailor-made Polymer Interfaces, Surfaces on Demand