Publications in Scientific Journals:
A. Daskalova, I. Bliznakova, A. Zhelyazkova, B. Ostrowska, A. Trifonov, I. Buchvarov, L. Avramov, W. Husinsky:
"Femtosecond laser surface texturing of 3D poly-ϵ-caprolactone matrices for bone tissue engineering applications";
Journal of Physics: Conference Series,
Fibrous 3D matrices were fabricated from poly-ɛ-caprolactone (PCL) by fused
deposition modeling. Femtosecond laser irradiation was then used to demonstrate the
possibility to affect the porosity of the 3D PCL fiber meshes. The surface characteristics were
analyzed by scanning electron microscopy (SEM) and confocal microscopy. The
interrelationship was examined between the laser processing parameters (number of pulses,
pulse energy applied) and the response of the biomaterial. The formation was demonstrated of
well-defined micropores, while the original fiber structure was retained. The study of cells
cultivation on the laser-modified scaffolds showed good adhesion compared to a non-modified
scaffold. The results obtained showed that femtosecond laser processing can be used as an
alternative non-contact tool in enhancing the porosity of artificial constructs, thus influencing
the cell adhesion into fibrous meshes.
Created from the Publication Database of the Vienna University of Technology.