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S. Najari, H. Bagheri, Z. Monsef-Khoshhesab, A. Hajian, A. Afkhami:
"Electrochemical sensor based on gold nanoparticle-multiwall carbon nanotube nanocomposite for the sensitive determination of docetaxel as an anticancer drug";
Ionics, 24 (2018), 3209 - 3219.

For the first time, a sensitive and selective method for determination of docetaxel (as an anti-cancer drug) at gold nanoparticle-
multiwall carbon nanotubes/glassy carbon electrode (Au-MWCNTs/GCE) was suggested using cyclic voltammetry and differ-
ential pulse anodic stripping voltammetry (DPASV) method. After the construction of the electrochemical sensor and optimiza-
tion of the effective parameters such as pH, accumulation time, and potential, the sensor was applied for the determination of
docetaxel in the range of 0.3 - 3.3 μ mol L
− 1
. The results show that Au-MWCNTs significantly catalyzed the redox reaction of
docetaxel during electrochemical detection. The limit of detection was estimated to be 90 nmol L
− 1
based on 3S b /m. The
performed studies showed that Au-MWCNTs/GCE has a good selectivity, sensitivity, and reproducibility. This sensor was used
to determine the docetaxel in real samples (human urine and human serum), and the obtained data illustrate that fabricated
electrochemical sensor is promising for use in routine analytical applications.

http://dx.doi.org/10.1007/s11581-018-2517-3