[Zurück]

L. Tytgat, S. Baudis, H. Ottevaere, R. Liska, H. Thienpont, P. Dubruel, S. Vlierberghe:
"Photopolymerizable Materials for Cell Encapsulation";
in: "3D Printing and Biofabrication", Springer Nature Switzerland AG. Part of Springer Nature, Switzerland, 2018, ISBN: 978-3-319-45443-6, S. 353 - 396.

Photopolymerization of hydrogels in the presence of cells is a frequently applied technique to realize tissue engineering and regeneration due to the fact that the reaction can take place under cell-friendly physiological conditions. Photopolymerization can be subdivided into three modes, including radical, cationic, and anionic photopolymerization, according to the reactive species which are formed during initiation and propagation. However, radical photoinitiators are the only species suitable for hydrogel formation since ionic photopolymerization inevitably leads to termination of the reactive species as a result of the presence of water. Hydrogels are promising materials due to their capability to absorb large amounts of water and biological fluids without dissolving, their ability to become photopolymerized in the presence of cells, and their close resemblance to the extracellular matrix of native tissue. The present chapter aims to provide an overview of commonly applied photoinitiators as well as photopolymerizable natural and synthetic polymers which are frequently used for cell encapsulation purposes.

Photopolymerization, 3D Printing, tissue engineering, cell-friendly physiological conditions, radical photoinitiators, hydrogel formation

http://dx.doi.org/10.1007/978-3-319-45444-3_15

https://link.springer.com/referenceworkentry/10.1007%2F978-3-319-45444-3_15