Zeitschriftenartikel:
N. Kratena, N. Biedermann, B. Stojanovic, L. Göschl, M. Weil, V. Enev, G. Gmeiner, P. Gärtner:
"Synthesis of a human long-term oxymetholone metabolite";
Steroids,
150
(2019),
10;
S. 108430.
Kurzfassung englisch:
A long-term metabolite of the doping agent oxymetholone (OXM-M2, 17β-hydroxymethyl-2,17α-methyl-18-norandrost-13-en-3-one) which has been identified by GC-MS/MS was synthesized from commercially available materials. Two efficient synthetic routes to access both C-17 epimers of tentative metabolites were developed. The identity and molecular configuration of the in vivo metabolite: 17β-hydroxymethyl-2α,17α-methyl-18-norandrost-13-en-3-one was confirmed by single crystal X-ray diffraction.
Schlagworte:
Long-term metabolite Oxymetholone Total synthesis
"Offizielle" elektronische Version der Publikation (entsprechend ihrem Digital Object Identifier - DOI)
http://dx.doi.org/10.1016/j.steroids.2019.108430
Erstellt aus der Publikationsdatenbank der Technischen Universität Wien.