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Zeitschriftenartikel:

M. Draskovits, H. Kalaus, C. Stanetty, M.D. Mihovilovic:
"Intercepted dehomologation of aldoses by N-heterocyclic carbene catalysis - a novel transformation in carbohydrate chemistry";
Chemical Communications, 55 (2019), 81; S. 12144 - 12147.



Kurzfassung englisch:
The development of an N-heterocyclic carbene (NHC) catalysed intercepted dehomologation of aldoses is reported. The unique selectivity of NHCs for aldehydes is exploited in the complex context of reducing sugars. Examples of strong substrate governance for either intercepted dehomologation or a subsequent redox-lactonisation were identified and mechanistically understood. More importantly, it was shown that catalyst design allowed the tuning of the selectivity of the reaction with structurally unbiased starting materials towards either of the two scenarios.

Schlagworte:
NHC, sugar


"Offizielle" elektronische Version der Publikation (entsprechend ihrem Digital Object Identifier - DOI)
http://dx.doi.org/10.1039/C9CC05906G

Elektronische Version der Publikation:
https://publik.tuwien.ac.at/files/publik_283329.pdf



Zugeordnete Projekte:
Projektleitung Christian Stanetty:
Kontrollierter Zuckerabbau durch N-Heterocyclische Carbene


Erstellt aus der Publikationsdatenbank der Technischen Universitšt Wien.