Vorträge und Posterpräsentationen (ohne Tagungsband-Eintrag):
R. Reichsöllner, L. Rebers, A. Southan, S. Baudis:
"Real Time-NIR-Photorheology: In Situ Characterization of the Gelatin-Methacryloyl Hydrogel Photocuring Process";
Vortrag: ViCEM - Vienna Center for Engineering in Medicine - Biennial Meeting 2019,
Wien;
14.11.2019
- 15.11.2019.
Kurzfassung englisch:
Real Time-NIR-Photorheology: In Situ Characterization of the Gelatin-Methacryloyl Hydrogel Photocuring Process
A combination of formulation cooling with photocrosslinking of gelatin-methacryloyl affects the gelation process and the properties of the resulting hydrogel, regardless of the respective GMA´s abilities to preform physical hydrogels.
. Cooling results in stiffer gels (G´) and higher final DBC.
. Lower temperatures decrease the photoreactivity (ΔDBC·Δt-1) but significantly accelerate the stiffness increase during photocrosslinking (ΔG`·Δt-1).
We hypothesize that dual-crosslinking produces stiffer hydrogels by two mechanisms: Firstly, formed physical interactions and superstructures like helices during cooling are stabilized by covalent crosslinking. Secondly, cooling induces the formation of methacryloyl-rich domains, resulting in a higher overall DBC.
Schlagworte:
gelatin-methacryloyl, gelation process, hydrogel, photoreactivity, photocrosslinking
Erstellt aus der Publikationsdatenbank der Technischen Universität Wien.