[Zurück]


Zeitschriftenartikel:

A. Abebe, Y. Bayeh, G. Tesfay, N.T. Madhu, W. Linert:
"Mono and Binuclear Cobalt(II) Mixed Ligand Complexes Containing 1,10- Phenanthroline and Adenine using 1,3-diaminopropane as a Spacer: Synthesis, Characterization and Antibacterial Activity Investigations";
Future Journal of Pharmaceutical Sciences, 6 (2020), 13; S. 1 - 9.



Kurzfassung englisch:
Background: Coordination compounds, in particular cobalt(II) mixed
ligand complexes containing 1,10-phenantroline have drawn the
attention of many investigators as some of them are showing
antimicrobial activities.
Result: Herein, we report three novel mixed ligand complexes of
cobalt(II) having the formulae [Co(L1)2(H2O)2]Cl2, [Co(L1)2(L2)(H2O)]Cl2
and [Co2(L1)4(L2)2(L3)]Cl4 (L1= 1,10-Phenanthroline, L2= Adenine, L3=
1,3-Diaminepropane), were synthesized and characterized by elemental
analysis, conductivity measurement, infrared and UV-Vis spectroscopic
techniques. Octahedral geometries are proposed to all the complexes. In
vitro antibacterial activities of the ligands, salt and metal complexes were
tested on four pathogenic bacteria (Staphylococcus aureus, Salmonella
typhus, Escherichia coli and Staphylococcus epidermis) using disc
diffusion method.
Conclusions: It is interesting to note that the newly synthesized
cobalt(II) complexes are active against gram negative bacteria
(Escherichia coli and Klebsiella pneumoniae) even though cobalt(II)
complexes are well known for their activity against gram positive
bacteria.

Schlagworte:
Binuclear; cobalt(II) complex; 1,10-phenanthroline; adenine; 1,3-diaminopropane; antibacterial activity


"Offizielle" elektronische Version der Publikation (entsprechend ihrem Digital Object Identifier - DOI)
http://dx.doi.org/10.1186/s43094-020-00030-4


Erstellt aus der Publikationsdatenbank der Technischen Universitšt Wien.