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P. Steinbauer, S. Orman, C. Hofstetter, M. Schwentenwein, G. Russmüller, J. Stampfl, R. Liska, S. Baudis:
"Patient-specific biocompatible polymer scaffolds for bone tissue regeneration";
Poster: 2020 TERMIS EU Abstracts, Manchester, online; 05-26-2020 - 05-29-2020; in: "2020 TERMIS EU Abstracts", e Cells und Materials, 2020, Collection 1 (2020), ISSN: 1473-2262; 308.

Additive manufacturing technologies (AMT´s) like digital light processing stereolithography (DLP-SLA) provide the opportunity to manufacture biocompatible patient specific materials for bone tissue engineering approaches.¹ Highly crosslinked state of the art materials based on (meth)acrylate resins cannot meet the high requirements regarding mechanical properties and biocompatibility. Novel vinyl ester (VE) monomer systems with considerably lower cytotoxicity and polyvinyl alcohol as favorable degradation product, emerge as promising biocompatible precursors for photopolymers.²⁻⁴ The established vinyl ester monomers are suitable for precisely manufactured and customized scaffolds for bone tissue regeneration. Photopolymers show very low toughness in general due to their characteristic polymer architecture. Nevertheless, by using toughness enhancers, high molecular weight co-monomers as well as chain transfer agents, toughness can be increased to ensure fixation of implants by screws.

tough 3D printable scaffolds, additive manufacturing technologies, digital light processing stereolithography, mechanical properties and biocompatibilitybone tissue engineering,