Publications in Scientific Journals:
N Berger, J. Gindlhuber, B Hirschmugl, R. Zimmermann, R. Birner-Grünberger, C Wadsack:
"PLACENTAL DAGL beta REGULATES 2-ARACHIDONOYLGLYCEROL (2-AG) LEVELS AND IS INVOLVED IN PREGNANCY INDUCED INFLAMMATION";
Placenta,
112
(2021),
000690357600132;
41 pages.
English abstract:
Diacylglycerollipase alpha/beta (DAGLα/β) are two sequence-related serine hydrolases, biosynthesizing 2-arachidonoylglycerol (2-AG). 2-AG, one of the main endocannabinoids, and its esterified fatty acid arachidonic acid serve as substrates for pro-inflammatory cellular pathways. Chronic inflammation is one hallmark of placentas affected by preeclampsia (PE) which is often linked to an altered lipid metabolism. In this study, we aim to identify the specific function and regulation of DAGLα/β in healthy (CTRL) and PE placentas.
"Official" electronic version of the publication (accessed through its Digital Object Identifier - DOI)
http://dx.doi.org/10.1016/j.placenta.2021.07.135
Electronic version of the publication:
https://publik.tuwien.ac.at/files/publik_302689.pdf
Created from the Publication Database of the Vienna University of Technology.