[Zurück]

J. Appenroth:
"Electrochemical manipulation of catechol reaction mechanisms";
Vortrag: Seminar Institut für Allgemeine Physik (IAP), TU Wien, Institut für Angewandte Physik; 21.06.2022.

Redox-active catechols, in particular L-DOPA and dopamine, are found in many adhesive biological systems. For example, in marine mussels L-DOPA containing byssus threads are shown to adhere to different substrates in harsh saline environments. Their oxidation and reduction can be driven both by pH changes and electrochemistry. While various models have been proposed, the exact reaction paths of these catechols remain a topic of discussion. To gain more insight into the dynamics and redox activity of catechols in aqueous solution their reaction paths and products were studied using electrochemistry and UV-vis. We further used this knowledge to develop a polymeric hydrogel that was electro-crosslinked and showed high adhesion compared to mussel foot proteins at the polymer/water interface.
By combining these methods, we are able to shed new light on the redox active behaviour of catechols.